Wilms Tumor Ppt New !!better!! -

This guide provides a structured framework for a modern PowerPoint presentation on Wilms Tumor (nephroblastoma), the most common kidney cancer in children Core Modules for a Wilms Tumor PPT 1. Introduction & Epidemiology Definition

: Wilms tumor is a malignant embryonic tumor of the kidney that accounts for about 90% of pediatric renal tumors. : Most commonly diagnosed in children aged 3 to 4 years , with 90% of cases appearing before age six. : Occurs in approximately 1 in 10,000 children globally. Risk Factors wilms tumor ppt new

: More frequent in African American children and slightly more common in girls. 2. Etiology & Pathogenesis Wilms Tumor - StatPearls - NCBI Bookshelf - NIH This guide provides a structured framework for a

Slide 9: Prognosis & Follow-up

  • Overall survival for favorable histology >90%.
  • Poor prognostic factors: diffuse anaplasia, advanced stage, age >10 years or <2 months.
  • Follow-up: Abdominal US every 3 months for 2 years, then annually; chest imaging if high risk.
  • Late effects: Secondary malignancies (especially after doxorubicin/radiation), cardiomyopathy, renal insufficiency.

Slide 1: Title Slide – The Modern Face of Wilms Tumor

Suggested Title: Wilms Tumor 2025: From Imaging to Immunotherapy Subtitle: Updates from COG and SIOP-RTSG Protocols Overall survival for favorable histology &gt;90%

Speaker Note: Begin with a case – a 3-year-old with an asymptomatic abdominal mass. This hooks the audience.

Slide 7: Staging (COG System) – Use a Table/Flowchart

| Stage | Description | |-------|-------------| | I | Tumor limited to kidney, completely resected, capsule intact. | | II | Tumor extends beyond kidney but completely resected (no residual). | | III | Residual non-hematogenous tumor post-op (e.g., positive margins, lymph node involvement). | | IV | Hematogenous metastases (lung, liver, bone, brain). | | V | Bilateral renal involvement at diagnosis. |